INHALATION & EXPOSURE CORE SERVICES - STAFF RESEARCH ASSOCIATE 3
RESPIRATORY DISEASES RESEARCH CENTER
University of California, Davis
Starting salary will be between $4,883.33 - $9,983.33/MO. Salary is determined based on qualifications and commensurate with experience.
Open Until Filled - For Consideration, Apply by 04-15-2018. This position is opened until filled.
The California National Primate Research Center, CNPRC, at UC Davis is an Organized Research Unit which conducts interdisciplinary research programs on significant human health problems where non-human primates is the animal model of choice. In addition to its major efforts in the area of research, the CNPRC is also committed to its missions of teaching and service.
The mission of the Inhalation Exposure Core is to provide a specialized platform for the investigation of health impacts resulting from the inhalable environment and evaluation of therapeutics for the mitigation of respiratory disease while serving as a valuable educational resource on the science and technology comprising this platform. The Inhalation Exposure Core provides short- and long-term generation, delivery, and analysis of precisely controlled atmospheres to investigate human health effects of environmental challenges using both in vitro and in vivo laboratory animal models.
INHALATION & EXPOSURE CORE SERVICES - STAFF RESEARCH ASSOCIATE 3
Under the direction of the Core Services Manager, serve as Core Technical Lead and support management for the day-to-day operations of the Inhalation Exposure Core. Manage workflow and recharge work activities that include rate development, business development support. Manage and submit core billing charges to Business Office. Provide technical design and set up/installation and testing exposure and PFT systems and/or the modification of existing systems (electrical and mechanical devices to support and advance the research goals and objectives of the CNPRC's mission.
Provide professional technical research support in specialized inhalation exposure methods (Agents of interest include but are not limited to allergen and bioaerosols, air pollutants and therapeutic compounds, and infectious agents) and research requiring PFT ranging from but not limited to design and fabrication, development, and implementation. Train and develop set up and perform a variety of technical and complex PFT methods (includes maintenance/repair and calibrations). Perform analysis of air samples from chambers or other sources as specified in lab protocols; upgrade software and hardware for existing data acquisition/system/data maintenance; and exposure record keeping and reporting. Compile and analyze data, generate reports, contribute to the technical writing of methods and results included in but not limited to grants and manuscripts.
Coordinate faculty-driven program/project activities in the development of proposed design project plans, and testing to meet individual project objectives. Apply test methodology in the design of testing and testing strategies for the analysis and qualification of fabricated devices, equipment, and systems. Define and track quality assurance metrics such as defect densities and other issues that can negatively impact research results. Plan and conduct the analysis, inspection, design, test, and/or integration to assure the quality of devices and equipment meet the operational needs of large-scale and complex research projects.
Assist PIs in drafting animal care and use protocols involving the facility. Interact with internal and external personnel on significant matters. Document facility activities for reports to the NIH and site visit groups. Coordinate all facility animal activities for nonhuman primates with the Center's Primate Resources. Coordinate rodent activities with TRACS.
-Master's Degree in mechanical or biomedical engineering from an accredited institution or the equivalent combination of education, training, and professional technical experience from which comparable skills can be acquired through prolonged study and on-the-job training.
-Experience in primatology with an emphasis on pulmonary physiology and adverse effects of exposures through inhalation and perfuming experimental pulmonary function testing.
-Experience performing pulmonary function tests in a variety of mammalian species (monkey, rodent).
-Experience using Apple and PC-based computer systems for data acquisition and analysis and software systems Excel, Sigma Plot.
-Experience in software programming environments of LabView and Matlab.
-Skill in applied experimental design and statistical analysis and using hardware and software of data acquisition systems.
-Experience applying mechanical ventilation techniques and aerosol administration.
-Technical skills to design, fabricate, operate, troubleshoot, and repair electrical and mechanical systems. Skills to calibrate and troubleshoot electronic equipment.
-Applied experience in inhalation exposure, exposure data acquisition systems, air pollutant analyzers, use of aerosol and gaseous air contaminants, use of animals including non-human primates and rodents, execution and conduct of complex long-term inhalation studies, and standard methods in air pollution monitoring. Experience in the applied knowledge of fluid handling systems, aerosols and the characteristics of materials.
-Knowledge and experience with mechanical device and instrumentation failure modes and risk analysis.
-Expertise in development, design, and operation of inhalation exposure chambers and other systems including those for generation and characterization of gas and aerosol test atmospheres.
-Facility management experience in a research setting that includes budget development and recharge/billing administration.
-Skills to guide and train students, postdocs, and lab personnel in all methods/techniques and concepts.
-Experience to communicate (verbal or written) complex and technical information to vendors, collaborators, investigators and to scientific staff.
-Experience using computerized data acquisition systems for PC and Macintosh platforms with a variety of software.
-Experience preparing written data summaries, writing manuscripts for publications, and other academic/scholarly reports.
-Skills to write IACUC protocols, laboratory SOP's, reports, data summaries and develop standardize training and devise plans/specs for testing models for animal experiments. Ability to write instruction sets, test plans and operating procedures and technical sections for grants.
-Experience developing or contributing towards cost estimates and project reports.
-Experience designing, installing, validating and maintaining hardware systems using standard industry tools (aerosol generators, sampling devices, exposure systems etc).
-Knowledge of fluid handling, aerosols and characteristics or materials; characterization of gaseous and aerosol test atmospheres; and standard methods in air pollution monitoring.
-Experience training, mentoring and guiding visiting scientists and technicians in the design, fabrication and operation of various inhalation systems (nose-only, head-only, whole-body exposure systems) and PFTs.
-Experience working in Good Laboratory Practices and FDA regulatory compliance requirements
-Extensive experience to plan, design, execute and manage research projects to meet project goals and deadlines. Expertise to manage in vivo as well as in vitro studies including knowledge to determine the feasibility of future studies and make recommendations and modifications to improve studies.
-Knowledge of biosafety and regulatory requirements, and IACUC protocols, and necessary training to participate in studies with these requirements.
-Knowledge of laboratory safety and proper use, handling, monitoring, measurement and disposal of radioisotopes, carcinogens, and biohazardous substances.
-Organizational skills to coordinate projects, data summary, and to accommodate changes in project needs, priorities, or deadlines as they arise.
-Skills to comprehend and respond to complex research needs including evaluation and implementation of new procedures and techniques, and to follow detailed technical protocols, published procedures, and equipment operations manuals.
-Communication skills to discuss and interpret technical matters a wide variety of individuals, and to understand requirements and instructions.
-Independent thinking and problem-solving skills for research and technical problems.
For full application instructions and position description, visit
The California National Primate Research Center (CNPRC) is an Affirmative Action/Equal Opportunity Educator & Employer (A.A./E.O.E.E.)
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